Publications
Real-time Scientific Visualization and Interactive Steering for High-Performance Computing Simulations
This document presents research on real-time visualization and interactive steering for high-performance computing simulations. By …
Simulation of non-spherical particles for managing mass flow within a belt-driven hopper
In this work, a discrete element method was used to investigate pellet-shaped granular flow within a bottom-driven conveyor belt as a …
Spatio-temporal analysis of shear traction dynamics on fish body surface
Fish swimming is a prominent research focus in biomimetic hydrodynamics, and studying the surface stress dynamic of fish contributes to …
Comparison of dynamic mode decomposition with other data-driven models for lung cancer incidence rate prediction
IntroductionPublic health data analysis is critical to understanding disease trends. Existing analysis methods struggle with the …
Stability analysis of moored floating offshore seamarks
In maritime channels, seamark is a critical navigation device that provides an aid to identify approximate positions of the sea area. …
Chimeric nanobody-decorated liposomes by self-assembly
Liposomes as drug vehicles have advantages, such as payload protection, tunable carrying capacity and improved biodistribution. …
Immersed force analysis of fish surface with carangiform locomotion
This paper investigates the immersed forces on a fish surface during carangiform locomotion. Numerical simulations were conducted and …
Implementation of a Two-Dimensional Finite-Element Fatigue Damage Model with Peridynamics to Simulate Crack Growth in a Compact Tension Specimen
The traditional finite element method (FEM) has limitations in accurately modeling crack propagation. Peridynamics, a nonlocal …
Dynamic Patterns and Modeling of Early COVID-19 Transmission by Dynamic Mode Decomposition
Preventing Chronic Disease (PCD) is a peer-reviewed electronic journal established by the National Center for Chronic Disease …
Immersed boundary-physics informed machine learning approach for fluid–solid coupling
Fluid–solid coupling is commonly used but sometimes expensive in large-scale simulations for fluid dynamics. Conventional numerical …
Toward Bi-directional In Situ Visualization and Analysis of Blood Flow Simulations With Dynamic Deforming Walls
We present some preliminary work toward bi-directional in situ visualization and analysis of blood flow considering blood cell …
Direct simulation of blood flow with heterogeneous cell suspensions in a patient-specific capillary network
Three-dimensional (3D) simulations on blood flow in a complex patient-specific retina vascular network were performed considering …
Flow pattern investigation of bionic fish by immersed boundary–lattice Boltzmann method and dynamic mode decomposition
The investigation of fish swimming is prevalent in the fields of biomimetic hydrodynamics and is important for research on the …
Interactive Virtual Reality Exploration of Large-Scale Datasets Using Omnidirectional Stereo Images
Virtual reality offers unique affordances that can benefit the scientific discovery process. However, virtual reality applications must …
Instrumenting Multiphysics Blood Flow Simulation Codes for In Situ Visualization and Analysis
Blood flow simulations have important applications in engineering and medicine, requiring visualization and analysis for both fluid …
Granular flow behavior in a conveyor system: From local velocity profiles to mass flow rates
Predictability of consistent granular flow is critical in many industries. This exploration of behavior in a conveyor apparatus aims to …
Simulation of circulating tumor cell transport and adhesion in cell suspensions in microfluidic devices
Understanding cell transport and adhesion dynamics under flow is important for many biotransport problems. We investigated the …
Label-free sorting of soft microparticles using a bioinspired synthetic cilia array
Isolating cells of interest from a heterogeneous population has been of critical importance in biological studies and clinical …
Facile Tumor Spheroids Formation in Large Quantity with Controllable Size and High Uniformity
A facile method for generation of tumor spheroids in large quantity with controllable size and high uniformity is presented. HCT-116 …
Numerical simulation of cell squeezing through a micropore by the immersed boundary method
The deformability of cells has been used as a biomarker to detect circulating tumor cells from patient blood sample using microfluidic …
Hemodynamic force triggers rapid NETosis within sterile thrombotic occlusions
Unlabelled BoxEssentials•Neutrophil extracellular traps (NETs) are generated during thrombosis and sepsis.•The effect of hemodynamics …
A parallel fluid–solid coupling model using LAMMPS and Palabos based on the immersed boundary method
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Nanoparticle transport and delivery in a heterogeneous pulmonary vasculature
Quantitative understanding of nanoparticles delivery in a complex vascular networks is very challenging because it involves interplay …
Mechanical Properties of Nanoworm Assembled by DNA and Nanoparticle Conjugates
Recently, DNA-nanoparticle conjugates have been widely used as building blocks for assembling complex nanostructures, due to their …
Characterization of Nanoparticle Dispersion in Red Blood Cell Suspension by the Lattice Boltzmann-Immersed Boundary Method
Nanodrug-carrier delivery in the blood stream is strongly influenced by nanoparticle (NP) dispersion. This paper presents a numerical …
Characterization of nanoparticle delivery in microcirculation using a microfluidic device
This work focuses on the characterization of particle delivery in microcirculation through a microfluidic device. In microvasculature …
Computational modeling of magnetic nanoparticle targeting to stent surface under high gradient field
A multi-physics model was developed to study the delivery of magnetic nanoparticles (MNPs) to the stent-implanted region under an …
Coupled particulate and continuum model for nanoparticle targeted delivery
Prediction of nanoparticle (NP) distribution in a vasculature involves transport phenomena at various scales and is crucial for the …
The influence of size, shape and vessel geometry on nanoparticle distribution
Nanoparticles (NPs) are emerging as promising carrier platforms for targeted drug delivery and imaging probes. To evaluate the delivery …
Capture, isolation and release of cancer cells with aptamer-functionalized glass bead array
Early detection and isolation of circulating tumor cells (CTC) can enable better prognosis for cancer patients. A Hele-Shaw device with …
The Shape of Things to Come: Importance of Design in Nanotechnology for Drug Delivery
The design of nanoparticle (NP) size, shape and surface chemistry has a significant impact on their performance. While the influences …
Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system
This research aims to develop targeted nanoparticles as drug carriers to the injured arterial wall under fluid shear stress by …
Influence of red blood cells on nanoparticle targeted delivery in microcirculation
Multifunctional nanomedicine holds considerable promise as the next generation of medicine that allows for targeted therapy with …
Capture, isolation and release of cancer cells with aptamer-functionalized glass bead array
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Velocity Effect on Aptamer-Based Circulating Tumor Cell Isolation in Microfluidic Devices
The isolation and detection of rare circulating tumor cells (CTCs) has been one of the focuses of intense research recently. In a …
A Hybrid Model for Nanoparticle Targeted Delivery in Blood Flow
Nanoparticle targeted delivery in vascular system involves the interplay of transport, hydrodynamic force, and multivalent interactions …